Mesopotamia is the tropical and green region of Northeast Argentina comprising of Misiones, Corrientes and Entre Rios provinces. Its name, meaning “between the rivers” in Greek, is derived from its being located between the Paraná River (on the southwest to north) and the Uruguay River (on the southeast to northeast). On this special self-drive journey you will travel from cosmopolitan Buenos Aires to the open wetlands of Iberá to the dense Atlantic Forest, via impressive Jesuit ruins and culminating with the incredible waterfalls of Iguazú. This itinerary would combine well with Mendoza (flying direct from Iguazu) or with any of our Brazil road trips.
Having a good, quality vehicle is key to every self-drive journey. We work carefully with our local team to source you the best vehicle available for your self-drive journey.
All our itineraries are tailor made, but here are some of our favourite routes and camp combinations.